MDMA/Ecstasy Research: Advances, Challenges, Future Directions
A Scientific Conference

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MDMA/Ecstasy Research: Advances, Challenges, Future Directions A Scientific Conference

This Conference was held at the Natcher Auditorium on the NIH Campus, July 19-20, 2001. Agenda Thursday, July 19, 2001 8:30 a.m. - 8:45 a.m. Welcome and Meeting Overview Glen R. Hanson, D.D.S., Ph.D. Director Division of Neuroscience and Behavioral Research National Institute on Drug Abuse [video - welcome][video - introduction] Alan I. Leshner, Ph.D. Director National Institute on Drug Abuse [video] 8:45 a.m. - 9:00 a.m. Keynote Addresses Ruth L. Kirschstein, M.D. Acting Director National Institutes of Health [video] The Honorable Tommy G. Thompson Secretary of Health and Human Services (invited) SESSION I: Patterns and Trends of MDMA Abuse: Implications for Prevention 9:00 a.m. - 9:15 a.m. Patterns and Trends of MDMA Abuse: Implications for Prevention Moderator:Jacques L. Normand, Ph.D. Acting Chief Epidemiology Research Branch National Institute on Drug Abuse [video] 9:15 a.m. - 9:35 a.m. Public Health Perspective on MDMA James N. Hall, B.A. Executive Director Up Front Drug Information Center Miami, Florida [video] 9:35 a.m. - 9:55 a.m. Patterns of MDMA Use Among Men Who Have Sex With Men in Boston and New York City Patricia Case, Sc.D. Director Program in Urban Health Department of Social Medicine Harvard Medical School Boston, Massachusetts [video] 9:55 a.m. - 10:15 a.m. Patterns and Trends of MDMA Use and Sexual Risk Behavior in Central Ohio Robert G. Carlson, Ph.D. Professor Center for Interventions, Treatment, and Addictions Research Wright State University School of Medicine Dayton, Ohio [video] 10:15 a.m. - 10:40 a.m. BREAK 10:40 a.m. - 11:00 a.m. The Diffusion of MDMA Use Among Urban Youth in Hartford, Connecticut; Implications for Drug and HIV Prevention in Club Drug Users and Their Networks Jean J. Schensul, Ph.D. Executive Director Institute for Community Research Hartford, Connecticut [video] 11:00 a.m. - 11:30 a.m. A Burning Candle: Challenges in Ecstasy Research Claire E. Sterk, Ph.D., Discussant Professor Department of Behavioral Sciences and Health Education Rollins School of Public Health Emory University Atlanta, Georgia [video] 11:30 a.m. - 12 noon Question and Answer Panel Moderator: Jacques L. Normand, Ph.D. Acting Chief Epidemiology Research Branch National Institute on Drug Abuse [video] 12 noon - 1:15 p.m. LUNCH (on your own) SESSION II: Acute Effects 1:15 p.m. - 1:30 p.m. Acute Effects Moderator: Jean Lud Cadet, M.D. Chief Molecular Neuropsychiatry Section Clinical Director Intramural Research Program National Institute on Drug Abuse [video] 1:30 p.m. - 2:00 p.m. Neurochemical Mediators and Neurophysiological Consequences of Acute MDMA Exposure in Rats Bryan K. Yamamoto, Ph.D. Professor of Psychiatry and Neurosciences Director Program in Basic and Clinical Neuroscience University Hospitals of Cleveland and Case Western Reserve University Cleveland, Ohio [video] 2:00 pm. - 2:30 p.m. The Acute Cardiovascular, Endocrine, and Pharmacokinetic Effects of MDMA in Humans John Mendelson, M.D. Associate Clinical Professor of Psychiatry and Medicine Drug Dependence Research Center Langley Porter Psychiatric Institute University of California at San Francisco San Francisco, California [video] 2:30 p.m. - 3:00 p.m. Subjective, Reinforcing, and Discriminative Stimulus Effects of MDMA in Humans Manuel E. Tancer, M.D. Associate Professor Departments of Psychiatry and Behavioral Neurosciences, and Pharmacology Wayne State University School of Medicine Detroit, Michigan [video] 3:00 p.m. - 3:30 p.m. BREAK 3:30 p.m. - 4:00 p.m. "Ecstasy" Deaths - More Than Just MDMA: An Australian Perspective Rodney J. Irvine, Ph.D. Research Fellow Department of Clinical and Experimental Pharmacology University of Adelaide Adelaide, Australia [video] 4:00 p.m. - 4:30 p.m. Acute Effects of MDMA: What Don't We Know? Gantt P. Galloway, Pharm.D, Discussant Chief of Pharmacological Research Haight Ashbury Free Clinics, Inc. San Francisco, California [video] 4:30 p.m. - 5:00 p.m. Question and Answer Panel Moderator: Jean Lud Cadet, M.D. Chief Molecular Neuropsychiatry Section Clinical Director Intramural Research Program National Institute on Drug Abuse [video] 5:00 p.m. - 6:30 p.m. POSTER PRESENTATIONS Friday, July 20, 2001 SESSION III: Long-Term Toxicology 8:30 a.m. - 8:45 a.m. Long-Term Toxicology Moderator: Steven Grant, Ph.D. Program Administrator Clinical Neurobiology Branch National Institute on Drug Abuse [video] 8:45 a.m. - 9:15 a.m. Overview of MDMA-induced Persistent Neurotoxicity: Preclinical Perspective Glen R. Hanson, D.D.S., Ph.D. Director Division of Neuroscience and Behavioral Research National Institute on Drug Abuse [video] 9:15 a.m. - 9:45 a.m. Developmental Effects of MDMA Charles V. Vorhees, Ph.D. Professor Division of Developmental Biology Children's Hospital Medical Center Cincinnati, Ohio [video] 9:45 a.m. - 10:15 a.m. MDMA-Induced Brain Serotonin Neurotoxicity: Preclinical Studies George A. Ricaurte, M.D., Ph.D. Associate Professor Department of Neurology Johns Hopkins University School of Medicine Baltimore, Maryland [video] 10:15 a.m. - 10:45 a.m. BREAK 10:45 a.m. - 11:15 a.m. Neuroimaging Studies in Chronic Effects of MDMA/Ecstasy Use Linda Chang, M.D. Scientist and Chair Medical Department Brookhaven National Laboratory Upton, New York [video] 11:15 a.m. - 11:45 a.m. Discussion, and Degeneration in Brain Following Binge Stimulants: All Dopaminergics Induce Degeneration in Fasciculus Retroflexus, but MDMA Also Induces Degeneration in Oral Pontine Serotonin Terminals Gaylord D. Ellison, Ph.D., Discussant Professor of Psychology and Neuroscience University of California at Los Angeles Los Angeles, California [video] 11:45 a.m. - 12:15 p.m. Question and Answer Panel Moderator: Steven Grant, Ph.D. Program Administrator Clinical Neurobiology Branch National Institute on Drug Abuse [video] 12:15 p.m. - 1:30 p.m. LUNCH SESSION IV: Long-Term Functional Consequences: Behavioral, Mood, Psychiatric, and Cognitive 1:30 p.m. - 1:45 p.m. Long-Term Functional Consequences: Behavioral, Mood, Psychiatric, and Cognitive Moderator: Minda R. Lynch, Ph.D. Acting Chief Behavioral and Cognitive Science Research Branch National Institute on Drug Abuse [video] 1:45 p.m. - 2:15 p.m. Neuropsychopathology Associated With MDMA Andy C. Parrott, Ph.D. Professor, Department of Psychology Head of the Recreational Drugs Research Group University of East London London, United Kingdom [video] 2:15 p.m. - 2:45 p.m. MDMA-Induced Brain Serotonin Neurotoxicity: Clinical Studies Una D. McCann, M.D. Associate Professor Behavioral Pharmacology Research Unit Johns Hopkins School of Medicine Baltimore, Maryland [video] 2:45 p.m. - 3:15 p.m. Long-Term Consequences of Ecstasy Use Upon Cognition Euphrosyne Gouzoulis-Mayfrank, M.D. Associate Professor Department of Psychiatry and Psychotherapy Medical Faculty of the University of Technology Aachen, Germany [video] 3:15 p.m. - 3:30 p.m. BREAK 3:30 p.m. - 4:00 p.m. Are the Psychological Problems Associated With Regular MDMA Use Reversed by Prolonged Abstinence? Michael John Morgan, Ph.D. Senior Lecturer Department of Experimental Psychology School of Biological Sciences University of Sussex, Falmer Brighton, United Kingdom [video] 4:00 p.m. - 4:30 p.m. Long-Term Functional Consequences of MDMA Abuse H. Valerie Curran, Ph.D., Discussant Professor of Psychopharmacology Sub-Department of Clinical Health Psychology University College London London, United Kingdom [video] 4:30 p.m. - 4:55 p.m. Question and Answer Panel Moderator: Minda R. Lynch, Ph.D. Acting Chief Behavioral and Cognitive Science Research Branch National Institute on Drug Abuse [video] 4:55 p.m. - 5:00 p.m. MDMA Research: What Next? Jerry Frankenheim, Ph.D., Conference Chair Pharmacologist and Program Official Pharmacology, Integrative and Cellular Research Branch National Institute on Drug Abuse [video] 5:00 p.m. ADJOURNMENT [MDMA Conference Program Index]

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